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Cholesterol absorption blocker ezetimibe prevents muscle wasting in severe dysferlin‐deficient and m...

Cholesterol absorption blocker ezetimibe prevents muscle wasting in severe dysferlin‐deficient and m...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1734f6d867e74b1188de0ce7c5e14a22

Cholesterol absorption blocker ezetimibe prevents muscle wasting in severe dysferlin‐deficient and mdx mice

About this item

Full title

Cholesterol absorption blocker ezetimibe prevents muscle wasting in severe dysferlin‐deficient and mdx mice

Publisher

Germany: John Wiley & Sons, Inc

Journal title

Journal of cachexia, sarcopenia and muscle, 2022-02, Vol.13 (1), p.544-560

Language

English

Formats

Publication information

Publisher

Germany: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

Background
Muscular dystrophy (MD) causes muscle wasting and is often lethal in patients due to a lack of proven therapies. In contrast, mouse models of MD are notoriously mild. We have previously shown severe human‐like muscle pathology in mdx [Duchenne MD (DMD)] and dysferlin‐deficient limb‐girdle MD type 2B (LGMD2B) mice by inactivating the g...

Alternative Titles

Full title

Cholesterol absorption blocker ezetimibe prevents muscle wasting in severe dysferlin‐deficient and mdx mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_1734f6d867e74b1188de0ce7c5e14a22

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1734f6d867e74b1188de0ce7c5e14a22

Other Identifiers

ISSN

2190-5991

E-ISSN

2190-6009

DOI

10.1002/jcsm.12879

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