Cholesterol absorption blocker ezetimibe prevents muscle wasting in severe dysferlin‐deficient and m...
Cholesterol absorption blocker ezetimibe prevents muscle wasting in severe dysferlin‐deficient and mdx mice
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Germany: John Wiley & Sons, Inc
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English
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Publisher
Germany: John Wiley & Sons, Inc
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Background
Muscular dystrophy (MD) causes muscle wasting and is often lethal in patients due to a lack of proven therapies. In contrast, mouse models of MD are notoriously mild. We have previously shown severe human‐like muscle pathology in mdx [Duchenne MD (DMD)] and dysferlin‐deficient limb‐girdle MD type 2B (LGMD2B) mice by inactivating the g...
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Cholesterol absorption blocker ezetimibe prevents muscle wasting in severe dysferlin‐deficient and mdx mice
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TN_cdi_doaj_primary_oai_doaj_org_article_1734f6d867e74b1188de0ce7c5e14a22
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1734f6d867e74b1188de0ce7c5e14a22
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ISSN
2190-5991
E-ISSN
2190-6009
DOI
10.1002/jcsm.12879