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Synthesis and Biological Activity Characterization of Novel 5-Oxopyrrolidine Derivatives with Promis...

Synthesis and Biological Activity Characterization of Novel 5-Oxopyrrolidine Derivatives with Promis...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1735c67cd5a34f67aea35ccb49123d48

Synthesis and Biological Activity Characterization of Novel 5-Oxopyrrolidine Derivatives with Promising Anticancer and Antimicrobial Activity

About this item

Full title

Synthesis and Biological Activity Characterization of Novel 5-Oxopyrrolidine Derivatives with Promising Anticancer and Antimicrobial Activity

Publisher

Basel: MDPI AG

Journal title

Pharmaceuticals (Basel, Switzerland), 2022-08, Vol.15 (8), p.970

Language

English

Formats

Publication information

Publisher

Basel: MDPI AG

More information

Scope and Contents

Contents

The 1-(4-acetamidophenyl)-5-oxopyrrolidine carboxylic acid was applied for synthesizing derivatives bearing azole, diazole, and hydrazone moieties in the molecule. Modification of an acetamide fragment to the free amino group afforded compounds with two functional groups, which enabled to provide a series of 4-substituted-1-(4-substituted phenyl)py...

Alternative Titles

Full title

Synthesis and Biological Activity Characterization of Novel 5-Oxopyrrolidine Derivatives with Promising Anticancer and Antimicrobial Activity

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_1735c67cd5a34f67aea35ccb49123d48

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1735c67cd5a34f67aea35ccb49123d48

Other Identifiers

ISSN

1424-8247

E-ISSN

1424-8247

DOI

10.3390/ph15080970

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