Inhibition of SYK and cSrc kinases can protect bone and cartilage in preclinical models of osteoarth...
Inhibition of SYK and cSrc kinases can protect bone and cartilage in preclinical models of osteoarthritis and rheumatoid arthritis
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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The pathophysiology of osteoarthritis (OA) includes the destruction of subchondral bone tissue and inflammation of the synovium. Thus, an effective disease-modifying treatment should act on both of these pathogenetic components. It is known that cSrc kinase is involved in bone and cartilage remodeling, and SYK kinase is associated with the inflamma...
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Inhibition of SYK and cSrc kinases can protect bone and cartilage in preclinical models of osteoarthritis and rheumatoid arthritis
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TN_cdi_doaj_primary_oai_doaj_org_article_1740dcc49eee45d28bf18dcd98f4e729
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1740dcc49eee45d28bf18dcd98f4e729
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-021-02568-6
