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Cofilactin filaments regulate filopodial structure and dynamics in neuronal growth cones

Cofilactin filaments regulate filopodial structure and dynamics in neuronal growth cones

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_17720a5e1eb647b8a08bdacb7717c937

Cofilactin filaments regulate filopodial structure and dynamics in neuronal growth cones

About this item

Full title

Cofilactin filaments regulate filopodial structure and dynamics in neuronal growth cones

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2022-05, Vol.13 (1), p.2439-2439, Article 2439

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Cofilin is best known for its ability to sever actin filaments and facilitate cytoskeletal recycling inside of cells, but at higher concentrations in vitro, cofilin stabilizes a more flexible, hyper-twisted state of actin known as “cofilactin”. While this filament state is well studied, a structural role for cofilactin in dynamic cellular processes...

Alternative Titles

Full title

Cofilactin filaments regulate filopodial structure and dynamics in neuronal growth cones

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_17720a5e1eb647b8a08bdacb7717c937

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_17720a5e1eb647b8a08bdacb7717c937

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-022-30116-x

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