Identification of drug modifiers for RYR1-related myopathy using a multi-species discovery pipeline
Identification of drug modifiers for RYR1-related myopathy using a multi-species discovery pipeline
About this item
Full title
Author / Creator
Publisher
England: eLife Science Publications, Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: eLife Science Publications, Ltd
Subjects
More information
Scope and Contents
Contents
Ryanodine receptor type I-related myopathies (RYR1-RMs) are a common group of childhood muscle diseases associated with severe disabilities and early mortality for which there are no available treatments. The goal of this study is to identify new therapeutic targets for RYR1-RMs. To accomplish this, we developed a discovery pipeline using nematode,...
Alternative Titles
Full title
Identification of drug modifiers for RYR1-related myopathy using a multi-species discovery pipeline
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_1795f5ef4d7b4774b2d8fdbc43a0cdaf
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1795f5ef4d7b4774b2d8fdbc43a0cdaf
Other Identifiers
ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.52946
