FNDC4 acts as an anti-inflammatory factor on macrophages and improves colitis in mice
FNDC4 acts as an anti-inflammatory factor on macrophages and improves colitis in mice
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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FNDC4 is a secreted factor sharing high homology with the exercise-associated myokine irisin (FNDC5). Here we report that
Fndc4
is robustly upregulated in several mouse models of inflammation as well as in human inflammatory conditions. Specifically,
FNDC4
levels are increased locally at inflamed sites of the intestine of inflammatory b...
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FNDC4 acts as an anti-inflammatory factor on macrophages and improves colitis in mice
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TN_cdi_doaj_primary_oai_doaj_org_article_17b58db1f2fe4257b1e5e50f6ef241f8
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_17b58db1f2fe4257b1e5e50f6ef241f8
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms11314
