Type I IFN exacerbates disease in tuberculosis-susceptible mice by inducing neutrophil-mediated lung...
Type I IFN exacerbates disease in tuberculosis-susceptible mice by inducing neutrophil-mediated lung inflammation and NETosis
About this item
Full title
Author / Creator
Moreira-Teixeira, Lúcia , Stimpson, Philippa J. , Stavropoulos, Evangelos , Hadebe, Sabelo , Chakravarty, Probir , Ioannou, Marianna , Aramburu, Iker Valle , Herbert, Eleanor , Priestnall, Simon L. , Suarez-Bonnet, Alejandro , Sousa, Jeremy , Fonseca, Kaori L. , Wang, Qian , Vashakidze, Sergo , Rodríguez-Martínez, Paula , Vilaplana, Cristina , Saraiva, Margarida , Papayannopoulos, Venizelos and O’Garra, Anne
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Tuberculosis (TB) is a leading cause of mortality due to infectious disease, but the factors determining disease progression are unclear. Transcriptional signatures associated with type I IFN signalling and neutrophilic inflammation were shown to correlate with disease severity in mouse models of TB. Here we show that similar transcriptional signat...
Alternative Titles
Full title
Type I IFN exacerbates disease in tuberculosis-susceptible mice by inducing neutrophil-mediated lung inflammation and NETosis
Authors, Artists and Contributors
Author / Creator
Stimpson, Philippa J.
Stavropoulos, Evangelos
Hadebe, Sabelo
Chakravarty, Probir
Ioannou, Marianna
Aramburu, Iker Valle
Herbert, Eleanor
Priestnall, Simon L.
Suarez-Bonnet, Alejandro
Sousa, Jeremy
Fonseca, Kaori L.
Wang, Qian
Vashakidze, Sergo
Rodríguez-Martínez, Paula
Vilaplana, Cristina
Saraiva, Margarida
Papayannopoulos, Venizelos
O’Garra, Anne
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_17bb66cf20aa478d882dee5a8fe9ffd3
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_17bb66cf20aa478d882dee5a8fe9ffd3
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-19412-6
