Myelinating Schwann cells ensheath multiple axons in the absence of E3 ligase component Fbxw7
Myelinating Schwann cells ensheath multiple axons in the absence of E3 ligase component Fbxw7
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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In the central nervous system (CNS), oligodendrocytes myelinate multiple axons; in the peripheral nervous system (PNS), Schwann cells (SCs) myelinate a single axon. Why are the myelinating potentials of these glia so fundamentally different? Here, we find that loss of
Fbxw7
, an E3 ubiquitin ligase component, enhances the myelinating potentia...
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Full title
Myelinating Schwann cells ensheath multiple axons in the absence of E3 ligase component Fbxw7
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TN_cdi_doaj_primary_oai_doaj_org_article_17c998c1a86747189f3f8c1962a53a63
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_17c998c1a86747189f3f8c1962a53a63
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-10881-y
