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Improving on polygenic scores across complex traits using select and shrink with summary statistics...

Improving on polygenic scores across complex traits using select and shrink with summary statistics...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_17d3eb6aa9614ebbb8e169af80d269e8

Improving on polygenic scores across complex traits using select and shrink with summary statistics (S4) and LDpred2

About this item

Full title

Improving on polygenic scores across complex traits using select and shrink with summary statistics (S4) and LDpred2

Publisher

England: BioMed Central Ltd

Journal title

BMC genomics, 2024-09, Vol.25 (1), p.878-12, Article 878

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

As precision medicine advances, polygenic scores (PGS) have become increasingly important for clinical risk assessment. Many methods have been developed to create polygenic models with increased accuracy for risk prediction. Our select and shrink with summary statistics (S4) PGS method has previously been shown to accurately predict the polygenic r...

Alternative Titles

Full title

Improving on polygenic scores across complex traits using select and shrink with summary statistics (S4) and LDpred2

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_17d3eb6aa9614ebbb8e169af80d269e8

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_17d3eb6aa9614ebbb8e169af80d269e8

Other Identifiers

ISSN

1471-2164

E-ISSN

1471-2164

DOI

10.1186/s12864-024-10706-3

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