Design of an equilibrative nucleoside transporter subtype 1 inhibitor for pain relief
Design of an equilibrative nucleoside transporter subtype 1 inhibitor for pain relief
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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The current opioid crisis urgently calls for developing non-addictive pain medications. Progress has been slow, highlighting the need to uncover targets with unique mechanisms of action. Extracellular adenosine alleviates pain by activating the adenosine A1 receptor (A1R). However, efforts to develop A1R agonists have faced obstacles. The equilibra...
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Design of an equilibrative nucleoside transporter subtype 1 inhibitor for pain relief
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TN_cdi_doaj_primary_oai_doaj_org_article_17fd281f386d4e04a2978f005211c9ff
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_17fd281f386d4e04a2978f005211c9ff
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2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-024-54914-7