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Design of an equilibrative nucleoside transporter subtype 1 inhibitor for pain relief

Design of an equilibrative nucleoside transporter subtype 1 inhibitor for pain relief

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_17fd281f386d4e04a2978f005211c9ff

Design of an equilibrative nucleoside transporter subtype 1 inhibitor for pain relief

About this item

Full title

Design of an equilibrative nucleoside transporter subtype 1 inhibitor for pain relief

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2024-12, Vol.15 (1), p.10738-17, Article 10738

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The current opioid crisis urgently calls for developing non-addictive pain medications. Progress has been slow, highlighting the need to uncover targets with unique mechanisms of action. Extracellular adenosine alleviates pain by activating the adenosine A1 receptor (A1R). However, efforts to develop A1R agonists have faced obstacles. The equilibra...

Alternative Titles

Full title

Design of an equilibrative nucleoside transporter subtype 1 inhibitor for pain relief

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_17fd281f386d4e04a2978f005211c9ff

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_17fd281f386d4e04a2978f005211c9ff

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-024-54914-7

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