TBC1D9 regulates TBK1 activation through Ca2+ signaling in selective autophagy
TBC1D9 regulates TBK1 activation through Ca2+ signaling in selective autophagy
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Contents
Invading microbial pathogens can be eliminated selectively by xenophagy. Ubiquitin-mediated autophagy receptors are phosphorylated by TANK-binding kinase 1 (TBK1) and recruited to ubiquitinated bacteria to facilitate autophagosome formation during xenophagy, but the molecular mechanism underlying TBK1 activation in response to microbial infection i...
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Full title
TBC1D9 regulates TBK1 activation through Ca2+ signaling in selective autophagy
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TN_cdi_doaj_primary_oai_doaj_org_article_181094b3d4dc4048b7968139d1016659
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_181094b3d4dc4048b7968139d1016659
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-14533-4
