Ca2+ dysregulation in cardiac stromal cells sustains fibro-adipose remodeling in Arrhythmogenic Card...
Ca2+ dysregulation in cardiac stromal cells sustains fibro-adipose remodeling in Arrhythmogenic Cardiomyopathy and can be modulated by flecainide
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London: BioMed Central Ltd
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English
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London: BioMed Central Ltd
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Background Cardiac mesenchymal stromal cells (C-MSC) were recently shown to differentiate into adipocytes and myofibroblasts to promote the aberrant remodeling of cardiac tissue that characterizes arrhythmogenic cardiomyopathy (ACM). A calcium (Ca.sup.2+) signaling dysfunction, mainly demonstrated in mouse models, is recognized as a mechanism impac...
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Ca2+ dysregulation in cardiac stromal cells sustains fibro-adipose remodeling in Arrhythmogenic Cardiomyopathy and can be modulated by flecainide
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TN_cdi_doaj_primary_oai_doaj_org_article_18182d2f699f4083af4d1ace0e1d0059
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_18182d2f699f4083af4d1ace0e1d0059
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ISSN
1479-5876
E-ISSN
1479-5876
DOI
10.1186/s12967-022-03742-8
