Therapeutic concentrations of calcineurin inhibitors do not deregulate glutathione redox balance in...
Therapeutic concentrations of calcineurin inhibitors do not deregulate glutathione redox balance in human renal proximal tubule cells
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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The calcineurin inhibitors (CNI) cyclosporine A and tacrolimus comprise the basis of immunosuppressive regimes in all solid organ transplantation. However, long-term or high exposure to CNI leads to histological and functional renal damage (CNI-associated nephrotoxicity). In the kidney, proximal tubule cells are the only cells that metabolize CNI a...
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Full title
Therapeutic concentrations of calcineurin inhibitors do not deregulate glutathione redox balance in human renal proximal tubule cells
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TN_cdi_doaj_primary_oai_doaj_org_article_18329ce096de4722ad0f2457df0856c3
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_18329ce096de4722ad0f2457df0856c3
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0250996
