Functional coupling between TRPV4 channel and TMEM16F modulates human trophoblast fusion
Functional coupling between TRPV4 channel and TMEM16F modulates human trophoblast fusion
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England: eLife Science Publications, Ltd
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English
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Publisher
England: eLife Science Publications, Ltd
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Contents
TMEM16F, a Ca
-activated phospholipid scramblase (CaPLSase), is critical for placental trophoblast syncytialization, HIV infection, and SARS-CoV2-mediated syncytialization, however, how TMEM16F is activated during cell fusion is unclear. Here, using trophoblasts as a model for cell fusion, we demonstrate that Ca
influx through the Ca
perme...
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Full title
Functional coupling between TRPV4 channel and TMEM16F modulates human trophoblast fusion
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TN_cdi_doaj_primary_oai_doaj_org_article_188cd88aef404e6bb7b35887032a65f2
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_188cd88aef404e6bb7b35887032a65f2
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.78840
