SPINK1-induced tumor plasticity provides a therapeutic window for chemotherapy in hepatocellular car...
SPINK1-induced tumor plasticity provides a therapeutic window for chemotherapy in hepatocellular carcinoma
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Author / Creator
Man, Ki-Fong , Zhou, Lei , Yu, Huajian , Lam, Ka-Hei , Cheng, Wei , Yu, Jun , Lee, Terence K. , Yun, Jing-Ping , Guan, Xin-Yuan , Liu, Ming and Ma, Stephanie
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Tumor lineage plasticity, considered a hallmark of cancer, denotes the phenomenon in which tumor cells co-opt developmental pathways to attain cellular plasticity, enabling them to evade targeted therapeutic interventions. However, the underlying molecular events remain largely elusive. Our recent study identified CD133/Prom1 in hepatocellular carc...
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Full title
SPINK1-induced tumor plasticity provides a therapeutic window for chemotherapy in hepatocellular carcinoma
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TN_cdi_doaj_primary_oai_doaj_org_article_189114a40a214121a5216f29753810f7
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_189114a40a214121a5216f29753810f7
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-023-43670-9