Mithramycin induces promoter reprogramming and differentiation of rhabdoid tumor
Mithramycin induces promoter reprogramming and differentiation of rhabdoid tumor
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Rhabdoid tumor (RT) is a pediatric cancer characterized by the inactivation of SMARCB1, a subunit of the SWI/SNF chromatin remodeling complex. Although this deletion is the known oncogenic driver, there are limited effective therapeutic options for these patients. Here we use unbiased screening of cell line panels to identify a heightened sensitivi...
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Mithramycin induces promoter reprogramming and differentiation of rhabdoid tumor
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TN_cdi_doaj_primary_oai_doaj_org_article_18bf94a3ea2d4e32b5861a62e60c62a8
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_18bf94a3ea2d4e32b5861a62e60c62a8
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ISSN
1757-4676
E-ISSN
1757-4684
DOI
10.15252/emmm.202012640
