Surface functionalization affects the retention and bio-distribution of orally administered mesoporo...
Surface functionalization affects the retention and bio-distribution of orally administered mesoporous silica nanoparticles in a colitis mouse model
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Besides the many advantages of oral drug administration, challenges like premature drug degradation and limited bioavailability in the gastro-intestinal tract (GIT) remain. A prolonged residence time in the GIT is beneficial for enhancing the therapeutic outcome when treating diseases associated with an increased intestinal clearance rate, like inf...
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Full title
Surface functionalization affects the retention and bio-distribution of orally administered mesoporous silica nanoparticles in a colitis mouse model
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TN_cdi_doaj_primary_oai_doaj_org_article_198c17b3a0674e07aabc4ae82a70674e
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_198c17b3a0674e07aabc4ae82a70674e
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-023-47445-6
