Adjuvant effects of combination monophosphoryl lipid A and poly I:C on antigen-specific immune respo...
Adjuvant effects of combination monophosphoryl lipid A and poly I:C on antigen-specific immune responses and protective efficacy of influenza vaccines
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London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Toll-like receptor (TLR) agonists improve vaccine immunogenicity and efficacy, but they are currently unlicensed as adjuvants in influenza vaccines. This study aimed to investigate whether a combination of monophosphoryl lipid A (MPL, a TLR4 agonist) and polyriboinosinic polyribocytidylic acid (poly I:C, a TLR3 agonist) can enhance the protective e...
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Full title
Adjuvant effects of combination monophosphoryl lipid A and poly I:C on antigen-specific immune responses and protective efficacy of influenza vaccines
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TN_cdi_doaj_primary_oai_doaj_org_article_1998ec98a2634de29632a099843474f3
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1998ec98a2634de29632a099843474f3
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-023-39210-6
