Reduced neuronal size and mTOR pathway activity in the Mecp2 A140V Rett syndrome mouse model
Reduced neuronal size and mTOR pathway activity in the Mecp2 A140V Rett syndrome mouse model
About this item
Full title
Author / Creator
Publisher
England: Faculty of 1000 Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: Faculty of 1000 Ltd
Subjects
More information
Scope and Contents
Contents
Rett syndrome (RTT) is a neurodevelopmental disorder caused by mutation in the X-linked
MECP2
gene, encoding methyl-CpG-binding protein 2. We have created a mouse model (
Mecp2
A140V “knock-in” mutant) expressing the recurrent human
MECP2
A140V mutation linked to an X-linked mental retardation/Rett syndrome phenotype. Morphologica...
Alternative Titles
Full title
Reduced neuronal size and mTOR pathway activity in the Mecp2 A140V Rett syndrome mouse model
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_19a95b32448446168edbbb76eb880986
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_19a95b32448446168edbbb76eb880986
Other Identifiers
ISSN
2046-1402
E-ISSN
2046-1402
DOI
10.12688/f1000research.8156.1
