Age-associated augmented renal clearance and low BMI trigger suboptimal vancomycin trough concentrat...
Age-associated augmented renal clearance and low BMI trigger suboptimal vancomycin trough concentrations in children with haematologic diseases: data of 1453 paediatric patients from 2017 to 2022
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London: BioMed Central Ltd
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English
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London: BioMed Central Ltd
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Background It is usually difficult for the trough concentration of vancomycin to reach the recommended lower limit of 10 mg/L per the label dose in the paediatric population. Moreover, children with haematologic diseases who suffer from neutropenia are more likely to have lower exposure of vancomycin, and the risk factors have been poorly explored....
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Age-associated augmented renal clearance and low BMI trigger suboptimal vancomycin trough concentrations in children with haematologic diseases: data of 1453 paediatric patients from 2017 to 2022
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TN_cdi_doaj_primary_oai_doaj_org_article_19c727fa231444e1baf520adb0a176b4
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_19c727fa231444e1baf520adb0a176b4
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ISSN
1471-2431
E-ISSN
1471-2431
DOI
10.1186/s12887-023-04288-4