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Age-associated augmented renal clearance and low BMI trigger suboptimal vancomycin trough concentrat...

Age-associated augmented renal clearance and low BMI trigger suboptimal vancomycin trough concentrat...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_19c727fa231444e1baf520adb0a176b4

Age-associated augmented renal clearance and low BMI trigger suboptimal vancomycin trough concentrations in children with haematologic diseases: data of 1453 paediatric patients from 2017 to 2022

About this item

Full title

Age-associated augmented renal clearance and low BMI trigger suboptimal vancomycin trough concentrations in children with haematologic diseases: data of 1453 paediatric patients from 2017 to 2022

Publisher

London: BioMed Central Ltd

Journal title

BMC pediatrics, 2023-10, Vol.23 (1), p.1-528, Article 528

Language

English

Formats

Publication information

Publisher

London: BioMed Central Ltd

More information

Scope and Contents

Contents

Background It is usually difficult for the trough concentration of vancomycin to reach the recommended lower limit of 10 mg/L per the label dose in the paediatric population. Moreover, children with haematologic diseases who suffer from neutropenia are more likely to have lower exposure of vancomycin, and the risk factors have been poorly explored....

Alternative Titles

Full title

Age-associated augmented renal clearance and low BMI trigger suboptimal vancomycin trough concentrations in children with haematologic diseases: data of 1453 paediatric patients from 2017 to 2022

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_19c727fa231444e1baf520adb0a176b4

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_19c727fa231444e1baf520adb0a176b4

Other Identifiers

ISSN

1471-2431

E-ISSN

1471-2431

DOI

10.1186/s12887-023-04288-4

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