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Biopreservation and reversal of oxidative injury during blood storage by a novel curcumin-based gel...

Biopreservation and reversal of oxidative injury during blood storage by a novel curcumin-based gel...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_19e41a33ccb14999b4620e094901a00b

Biopreservation and reversal of oxidative injury during blood storage by a novel curcumin-based gel formulation

About this item

Full title

Biopreservation and reversal of oxidative injury during blood storage by a novel curcumin-based gel formulation

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2024-12, Vol.14 (1), p.31441-15, Article 31441

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Blood storage lesion induces cytosolic and membrane changes driven in part by hemoglobin (Hb) oxidation reactions within red blood cells (RBCs). A novel gel formulation containing the antioxidant curcuminoids in a biocompatible solvent system was used to deliver curcumin into RBCs. Incubation of peroxide treated RBCs stored in PBS with curcumin gel...

Alternative Titles

Full title

Biopreservation and reversal of oxidative injury during blood storage by a novel curcumin-based gel formulation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_19e41a33ccb14999b4620e094901a00b

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_19e41a33ccb14999b4620e094901a00b

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-024-82943-1

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