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Quantitative prediction of conditional vulnerabilities in regulatory and metabolic networks using PR...

Quantitative prediction of conditional vulnerabilities in regulatory and metabolic networks using PR...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_19f9589264d743d8835653ceef70aa7a

Quantitative prediction of conditional vulnerabilities in regulatory and metabolic networks using PRIME

About this item

Full title

Quantitative prediction of conditional vulnerabilities in regulatory and metabolic networks using PRIME

Publisher

London: Nature Publishing Group UK

Journal title

NPJ systems biology and applications, 2021-12, Vol.7 (1), p.43-11, Article 43

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The ability of
Mycobacterium tuberculosis
(Mtb) to adopt heterogeneous physiological states underlies its success in evading the immune system and tolerating antibiotic killing. Drug tolerant phenotypes are a major reason why the tuberculosis (TB) mortality rate is so high, with over 1.8 million deaths annually. To develop new TB therapeutics...

Alternative Titles

Full title

Quantitative prediction of conditional vulnerabilities in regulatory and metabolic networks using PRIME

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_19f9589264d743d8835653ceef70aa7a

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_19f9589264d743d8835653ceef70aa7a

Other Identifiers

ISSN

2056-7189

E-ISSN

2056-7189

DOI

10.1038/s41540-021-00205-6

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