A Spleen‐Targeted Tolerogenic mRNA‐LNPs Vaccine for the Treatment of Experimental Asthma
A Spleen‐Targeted Tolerogenic mRNA‐LNPs Vaccine for the Treatment of Experimental Asthma
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Author / Creator
Wang, Fazhan , Lou, Jia , Lou, Xiaohan , Wu, Fang , Gao, Xiaoke , Yao, Xiaohan , Wan, Jiajia , Duan, Xixi , Deng, Wenjing , Ma, Lixia , Zhang, Lijing , He, Guangjie , Wang, Ming , Ni, Chen , Lei, Ningjing and Qin, Zhihai
Publisher
Germany: John Wiley & Sons, Inc
Journal title
Language
English
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Publication information
Publisher
Germany: John Wiley & Sons, Inc
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Scope and Contents
Contents
Lipid nanoparticles (LNPs)‐based mRNA vaccines have witnessed their great advantages in the fight against infectious diseases. However, the pro‐inflammatory properties of mRNA‐LNPs vaccines may hinder the induction of antigen‐specific tolerogenic immune responses. Here, it is demonstrated that stearic acid‐doped LNPs co‐loaded with nucleoside‐modif...
Alternative Titles
Full title
A Spleen‐Targeted Tolerogenic mRNA‐LNPs Vaccine for the Treatment of Experimental Asthma
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_1a96fd2053dc4c0494668c077fa7ec5e
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1a96fd2053dc4c0494668c077fa7ec5e
Other Identifiers
ISSN
2198-3844
E-ISSN
2198-3844
DOI
10.1002/advs.202412543
