Differential utilization of ketone bodies by neurons and glioma cell lines: a rationale for ketogeni...
Differential utilization of ketone bodies by neurons and glioma cell lines: a rationale for ketogenic diet as experimental glioma therapy
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England: BioMed Central Ltd
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English
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England: BioMed Central Ltd
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Even in the presence of oxygen, malignant cells often highly depend on glycolysis for energy generation, a phenomenon known as the Warburg effect. One strategy targeting this metabolic phenotype is glucose restriction by administration of a high-fat, low-carbohydrate (ketogenic) diet. Under these conditions, ketone bodies are generated serving as a...
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Differential utilization of ketone bodies by neurons and glioma cell lines: a rationale for ketogenic diet as experimental glioma therapy
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TN_cdi_doaj_primary_oai_doaj_org_article_1a9c0f289be542f8a6d2fe6a0f3212ec
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1a9c0f289be542f8a6d2fe6a0f3212ec
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1471-2407
E-ISSN
1471-2407
DOI
10.1186/1471-2407-11-315