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HDAC6 inhibition disrupts HDAC6-P300 interaction reshaping the cancer chromatin landscape

HDAC6 inhibition disrupts HDAC6-P300 interaction reshaping the cancer chromatin landscape

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1aee7acab3d541f682bf1fe58ec3c016

HDAC6 inhibition disrupts HDAC6-P300 interaction reshaping the cancer chromatin landscape

About this item

Full title

HDAC6 inhibition disrupts HDAC6-P300 interaction reshaping the cancer chromatin landscape

Publisher

Germany: BioMed Central Ltd

Journal title

Clinical epigenetics, 2024-08, Vol.16 (1), p.109-20, Article 109

Language

English

Formats

Publication information

Publisher

Germany: BioMed Central Ltd

More information

Scope and Contents

Contents

Histone deacetylases (HDACs) are crucial regulators of gene expression, DNA synthesis, and cellular processes, making them essential targets in cancer research. HDAC6, specifically, influences protein stability and chromatin dynamics. Despite HDAC6's potential therapeutic value, its exact role in gene regulation and chromatin remodeling needs furth...

Alternative Titles

Full title

HDAC6 inhibition disrupts HDAC6-P300 interaction reshaping the cancer chromatin landscape

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_1aee7acab3d541f682bf1fe58ec3c016

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1aee7acab3d541f682bf1fe58ec3c016

Other Identifiers

ISSN

1868-7083,1868-7075

E-ISSN

1868-7083

DOI

10.1186/s13148-024-01725-8

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