Log in to save to my catalogue

Daratumumab in the Treatment of Light-Chain (AL) Amyloidosis

Daratumumab in the Treatment of Light-Chain (AL) Amyloidosis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1afdb865742b4785b3a47a10b8e43e4e

Daratumumab in the Treatment of Light-Chain (AL) Amyloidosis

About this item

Full title

Daratumumab in the Treatment of Light-Chain (AL) Amyloidosis

Publisher

Switzerland: MDPI

Journal title

Cells (Basel, Switzerland), 2021-03, Vol.10 (3), p.545

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI

More information

Scope and Contents

Contents

Systemic light-chain (AL) amyloidosis is caused by a small B cell, most commonly a plasma cell (PC), clone that produces toxic light chains (LC) that cause organ dysfunction and deposits in tissues. Due to the production of amyloidogenic, misfolded LC, AL PCs display peculiar biologic features. The small, indolent plasma cell clone is an ideal targ...

Alternative Titles

Full title

Daratumumab in the Treatment of Light-Chain (AL) Amyloidosis

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_1afdb865742b4785b3a47a10b8e43e4e

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1afdb865742b4785b3a47a10b8e43e4e

Other Identifiers

ISSN

2073-4409

E-ISSN

2073-4409

DOI

10.3390/cells10030545

How to access this item