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Topologically associating domains are ancient features that coincide with Metazoan clusters of extre...

Topologically associating domains are ancient features that coincide with Metazoan clusters of extre...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1b04c3b1a6a64b378ed9795e790183ff

Topologically associating domains are ancient features that coincide with Metazoan clusters of extreme noncoding conservation

About this item

Full title

Topologically associating domains are ancient features that coincide with Metazoan clusters of extreme noncoding conservation

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2017-09, Vol.8 (1), p.441-13, Article 441

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Developmental genes in metazoan genomes are surrounded by dense clusters of conserved noncoding elements (CNEs). CNEs exhibit unexplained extreme levels of sequence conservation, with many acting as developmental long-range enhancers. Clusters of CNEs define the span of regulatory inputs for many important developmental regulators and have been des...

Alternative Titles

Full title

Topologically associating domains are ancient features that coincide with Metazoan clusters of extreme noncoding conservation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_1b04c3b1a6a64b378ed9795e790183ff

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1b04c3b1a6a64b378ed9795e790183ff

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-017-00524-5

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