ISGylation controls exosome secretion by promoting lysosomal degradation of MVB proteins
ISGylation controls exosome secretion by promoting lysosomal degradation of MVB proteins
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Publisher
London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Contents
Exosomes are vesicles secreted to the extracellular environment through fusion with the plasma membrane of specific endosomes called multivesicular bodies (MVB) and mediate cell-to-cell communication in many biological processes. Posttranslational modifications are involved in the sorting of specific proteins into exosomes. Here we identify ISGylat...
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ISGylation controls exosome secretion by promoting lysosomal degradation of MVB proteins
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TN_cdi_doaj_primary_oai_doaj_org_article_1b2e7f717e724460ac0843fd8652dd65
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1b2e7f717e724460ac0843fd8652dd65
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms13588
