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CDR1 Composition Can Affect Nanobody Recombinant Expression Yields

CDR1 Composition Can Affect Nanobody Recombinant Expression Yields

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1b368566f33847f3bf9d116fff623bf4

CDR1 Composition Can Affect Nanobody Recombinant Expression Yields

About this item

Full title

CDR1 Composition Can Affect Nanobody Recombinant Expression Yields

Publisher

Switzerland: MDPI AG

Journal title

Biomolecules (Basel, Switzerland), 2021-09, Vol.11 (9), p.1362

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

The isolation of nanobodies from pre-immune libraries by means of biopanning is a straightforward process. Nevertheless, the recovered candidates often require optimization to improve some of their biophysical characteristics. In principle, CDRs are not mutated because they are likely to be part of the antibody paratope, but in this work, we descri...

Alternative Titles

Full title

CDR1 Composition Can Affect Nanobody Recombinant Expression Yields

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_1b368566f33847f3bf9d116fff623bf4

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1b368566f33847f3bf9d116fff623bf4

Other Identifiers

ISSN

2218-273X

E-ISSN

2218-273X

DOI

10.3390/biom11091362

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