VPAC1 and VPAC2 receptors mediate tactile hindpaw hypersensitivity and carotid artery dilatation ind...
VPAC1 and VPAC2 receptors mediate tactile hindpaw hypersensitivity and carotid artery dilatation induced by PACAP38 in a migraine relevant mouse model
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Milan: Springer Milan
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Language
English
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Milan: Springer Milan
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Background
Pituitary adenylate cyclase-activating peptide (PACAP) is a neuropeptide pivotal in migraine pathophysiology and is considered a promising new migraine drug target. Although intravenous PACAP triggers migraine attacks and a recent phase II trial with a PACAP-inhibiting antibody showed efficacy in migraine prevention, targeting the PAC...
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Full title
VPAC1 and VPAC2 receptors mediate tactile hindpaw hypersensitivity and carotid artery dilatation induced by PACAP38 in a migraine relevant mouse model
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TN_cdi_doaj_primary_oai_doaj_org_article_1b5638b4204d4c57a3832603fc0281f0
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1b5638b4204d4c57a3832603fc0281f0
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ISSN
1129-2377,1129-2369
E-ISSN
1129-2377
DOI
10.1186/s10194-024-01830-2
