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The structural basis of function and regulation of neuronal cotransporters NKCC1 and KCC2

The structural basis of function and regulation of neuronal cotransporters NKCC1 and KCC2

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1b5dcbea19614a15900e1d27bebbbc65

The structural basis of function and regulation of neuronal cotransporters NKCC1 and KCC2

About this item

Full title

The structural basis of function and regulation of neuronal cotransporters NKCC1 and KCC2

Publisher

London: Nature Publishing Group UK

Journal title

Communications biology, 2021-02, Vol.4 (1), p.226-226, Article 226

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

NKCC and KCC transporters mediate coupled transport of Na
+
+K
+
+Cl

and K
+
+Cl

across the plasma membrane, thus regulating cell Cl

concentration and cell volume and playing critical roles in transepithelial salt and water transport and in neuronal excitability. The function of these transporters has been...

Alternative Titles

Full title

The structural basis of function and regulation of neuronal cotransporters NKCC1 and KCC2

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_1b5dcbea19614a15900e1d27bebbbc65

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1b5dcbea19614a15900e1d27bebbbc65

Other Identifiers

ISSN

2399-3642

E-ISSN

2399-3642

DOI

10.1038/s42003-021-01750-w

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