The structural basis of function and regulation of neuronal cotransporters NKCC1 and KCC2
The structural basis of function and regulation of neuronal cotransporters NKCC1 and KCC2
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Contents
NKCC and KCC transporters mediate coupled transport of Na
+
+K
+
+Cl
−
and K
+
+Cl
−
across the plasma membrane, thus regulating cell Cl
−
concentration and cell volume and playing critical roles in transepithelial salt and water transport and in neuronal excitability. The function of these transporters has been...
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Full title
The structural basis of function and regulation of neuronal cotransporters NKCC1 and KCC2
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TN_cdi_doaj_primary_oai_doaj_org_article_1b5dcbea19614a15900e1d27bebbbc65
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1b5dcbea19614a15900e1d27bebbbc65
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ISSN
2399-3642
E-ISSN
2399-3642
DOI
10.1038/s42003-021-01750-w