Genetic mapping of cell type specificity for complex traits
Genetic mapping of cell type specificity for complex traits
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Single-cell RNA sequencing (scRNA-seq) data allows to create cell type specific transcriptome profiles. Such profiles can be aligned with genome-wide association studies (GWASs) to implicate cell type specificity of the traits. Current methods typically rely only on a small subset of available scRNA-seq datasets, and integrating multiple datasets i...
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Genetic mapping of cell type specificity for complex traits
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TN_cdi_doaj_primary_oai_doaj_org_article_1b79e2c2d7734c8abaf4baac708ba480
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1b79e2c2d7734c8abaf4baac708ba480
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-11181-1