Subcellular targeting and dynamic regulation of PTEN: implications for neuronal cells and neurologic...
Subcellular targeting and dynamic regulation of PTEN: implications for neuronal cells and neurological disorders
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Switzerland: Frontiers Research Foundation
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Language
English
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Switzerland: Frontiers Research Foundation
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PTEN is a lipid and protein phosphatase that regulates a diverse range of cellular mechanisms. PTEN is mainly present in the cytosol and transiently associates with the plasma membrane to dephosphorylate PI(3,4,5)P3, thereby antagonizing the PI3-Kinase signaling pathway. Recently, PTEN has been shown to associate also with organelles such as the en...
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Full title
Subcellular targeting and dynamic regulation of PTEN: implications for neuronal cells and neurological disorders
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TN_cdi_doaj_primary_oai_doaj_org_article_1b891d50c17a496fa640fedec9693a67
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1b891d50c17a496fa640fedec9693a67
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ISSN
1662-5099
E-ISSN
1662-5099
DOI
10.3389/fnmol.2014.00023
