FTO suppresses glycolysis and growth of papillary thyroid cancer via decreasing stability of APOE mR...
FTO suppresses glycolysis and growth of papillary thyroid cancer via decreasing stability of APOE mRNA in an N6-methyladenosine-dependent manner
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Huang, Jiapeng , Sun, Wei , Wang, Zhihong , Lv, Chengzhou , Zhang, Ting , Zhang, Dalin , Dong, Wenwu , Shao, Liang , He, Liang , Ji, Xiaoyu , Zhang, Ping and Zhang, Hao
Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
N6-methyladenosine (m
A) modification is the most common chemical modification in mammalian mRNAs, and it plays important roles by regulating several cellular processes. Previous studies report that m
A is implicated in modulating tumorigenesis and progression. However, dysregulation of m
A modification and effect of m
A demethylase fat...
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Full title
FTO suppresses glycolysis and growth of papillary thyroid cancer via decreasing stability of APOE mRNA in an N6-methyladenosine-dependent manner
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TN_cdi_doaj_primary_oai_doaj_org_article_1b8b0d72d33f4abc8f860dcd76a87d9b
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1b8b0d72d33f4abc8f860dcd76a87d9b
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ISSN
1756-9966,0392-9078
E-ISSN
1756-9966
DOI
10.1186/s13046-022-02254-z