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Monocyte Activation Test (MAT) as a possibility of replacement for the rabbit pyrogen test in hyperi...

Monocyte Activation Test (MAT) as a possibility of replacement for the rabbit pyrogen test in hyperi...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1c57bb3fd3fc40f5a95eafd7f3bda77c

Monocyte Activation Test (MAT) as a possibility of replacement for the rabbit pyrogen test in hyperimmune sera

About this item

Full title

Monocyte Activation Test (MAT) as a possibility of replacement for the rabbit pyrogen test in hyperimmune sera

Publisher

Sao Paulo: Universidade de Sao Paulo Faculdade de Ciencias

Journal title

Brazilian Journal of Pharmaceutical Sciences, 2018-01, Vol.54 (2)

Language

English

Formats

Publication information

Publisher

Sao Paulo: Universidade de Sao Paulo Faculdade de Ciencias

More information

Scope and Contents

Contents

The use of a commercial kit for the monocyte-activation test (MAT) was evaluated for assessing pyrogenic contamination of hyperimmune sera . Three batches of sera, two pyrogen free and one pyrogenic, were tested. Endotoxin spike recover indicated that sample dilutions from 1/2 to 1/10 are suitable. Kit transport and storage conditions were also eva...

Alternative Titles

Full title

Monocyte Activation Test (MAT) as a possibility of replacement for the rabbit pyrogen test in hyperimmune sera

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_1c57bb3fd3fc40f5a95eafd7f3bda77c

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1c57bb3fd3fc40f5a95eafd7f3bda77c

Other Identifiers

ISSN

2175-9790,1984-8250

E-ISSN

2175-9790

DOI

10.1590/s2175-97902018000217530

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