Tumour-vasculature development via endothelial-to-mesenchymal transition after radiotherapy controls...
Tumour-vasculature development via endothelial-to-mesenchymal transition after radiotherapy controls CD44v6+ cancer cell and macrophage polarization
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
It remains controversial whether targeting tumour vasculature can improve radiotherapeutic efficacy. We report that radiation-induced endothelial-to-mesenchymal transition (EndMT) leads to tumour vasculature with abnormal SMA
+
NG2
+
pericyte recruitment during tumour regrowth after radiotherapy.
Trp53
(but not
Tgfbr2
) dele...
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Full title
Tumour-vasculature development via endothelial-to-mesenchymal transition after radiotherapy controls CD44v6+ cancer cell and macrophage polarization
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TN_cdi_doaj_primary_oai_doaj_org_article_1c8be8c45157487b80a64a318466f67b
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1c8be8c45157487b80a64a318466f67b
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-07470-w
