CYP450 phenotyping and accurate mass identification of metabolites of the 8-aminoquinoline, anti-mal...
CYP450 phenotyping and accurate mass identification of metabolites of the 8-aminoquinoline, anti-malarial drug primaquine
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
The 8-aminoquinoline (8AQ) drug primaquine (PQ) is currently the only approved drug effective against the persistent liver stage of the hypnozoite forming strains Plasmodium vivax and Plasmodium ovale as well as Stage V gametocytes of Plasmodium falciparum. To date, several groups have investigated the toxicity observed in the 8AQ class, however, e...
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Full title
CYP450 phenotyping and accurate mass identification of metabolites of the 8-aminoquinoline, anti-malarial drug primaquine
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TN_cdi_doaj_primary_oai_doaj_org_article_1c94ac45b6e04f0888bb7f4518a68733
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1c94ac45b6e04f0888bb7f4518a68733
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ISSN
1475-2875
E-ISSN
1475-2875
DOI
10.1186/1475-2875-11-259
