Primary cilia on muscle stem cells are critical to maintain regenerative capacity and are lost durin...
Primary cilia on muscle stem cells are critical to maintain regenerative capacity and are lost during aging
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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During aging, the regenerative capacity of muscle stem cells (MuSCs) decreases, diminishing the ability of muscle to repair following injury. We found that the ability of MuSCs to regenerate is regulated by the primary cilium, a cellular protrusion that serves as a sensitive sensory organelle. Abolishing MuSC cilia inhibited MuSC proliferation in v...
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Full title
Primary cilia on muscle stem cells are critical to maintain regenerative capacity and are lost during aging
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TN_cdi_doaj_primary_oai_doaj_org_article_1cb547b9df374953936e2d5fd08f29bc
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1cb547b9df374953936e2d5fd08f29bc
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-022-29150-6
