A Novel Class of FKBP12 Ligands Rescues Premature Aging Phenotypes Associated with Myotonic Dystroph...
A Novel Class of FKBP12 Ligands Rescues Premature Aging Phenotypes Associated with Myotonic Dystrophy Type 1
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Switzerland: MDPI AG
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English
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Switzerland: MDPI AG
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Background: Myotonic dystrophy type 1 (DM1) is an autosomal dominant disorder clinically characterized by progressive muscular weakness and multisystem degeneration, which correlates with the size of CTG expansion and MBLN decrease. These changes induce a calcium and redox homeostasis imbalance in several models that recapitulate the features of pr...
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A Novel Class of FKBP12 Ligands Rescues Premature Aging Phenotypes Associated with Myotonic Dystrophy Type 1
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TN_cdi_doaj_primary_oai_doaj_org_article_1cc7a31eb0c24417ac30220d46bf4edd
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1cc7a31eb0c24417ac30220d46bf4edd
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ISSN
2073-4409
E-ISSN
2073-4409
DOI
10.3390/cells13231939
