Characterizing a thermostable Cas9 for bacterial genome editing and silencing
Characterizing a thermostable Cas9 for bacterial genome editing and silencing
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
CRISPR-Cas9-based genome engineering tools have revolutionized fundamental research and biotechnological exploitation of both eukaryotes and prokaryotes. However, the mesophilic nature of the established Cas9 systems does not allow for applications that require enhanced stability, including engineering at elevated temperatures. Here we identify and...
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Full title
Characterizing a thermostable Cas9 for bacterial genome editing and silencing
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TN_cdi_doaj_primary_oai_doaj_org_article_1d2d2fee1e3d44708bd22d9330e108c2
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1d2d2fee1e3d44708bd22d9330e108c2
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-017-01591-4
