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σ2R/TMEM97 in retinal ganglion cell degeneration

σ2R/TMEM97 in retinal ganglion cell degeneration

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1d3b2f964175428cacf0b3d8c79c728f

σ2R/TMEM97 in retinal ganglion cell degeneration

About this item

Full title

σ2R/TMEM97 in retinal ganglion cell degeneration

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2022-12, Vol.12 (1), p.20753-11, Article 20753

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The sigma 2 receptor (σ
2
R) was recently identified as an endoplasmic reticulum (ER) membrane protein known as transmembrane protein 97 (TMEM97). Studies have shown that σ
2
R/TMEM97 binding compounds are neuroprotective, suggesting a role of σ
2
R/TMEM97 in neurodegenerative processes. To understand the function of σ
2
R/T...

Alternative Titles

Full title

σ2R/TMEM97 in retinal ganglion cell degeneration

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_1d3b2f964175428cacf0b3d8c79c728f

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1d3b2f964175428cacf0b3d8c79c728f

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-022-24537-3

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