Angiosarcoma heterogeneity and potential therapeutic vulnerability to immune checkpoint blockade: in...
Angiosarcoma heterogeneity and potential therapeutic vulnerability to immune checkpoint blockade: insights from genomic sequencing
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Angiosarcoma is an aggressive tumor. Recent case series describe exceptional responses to checkpoint blockade in this disease.
Herein, we explored the genomic correlates of 48 angiosarcomas from the Angiosarcoma Project (12,499 variants analyzed in 6603 genes; whole-exome sequencing) versus 10,106 pan-cancer tumors in The Cancer Genome Atlas inc...
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Full title
Angiosarcoma heterogeneity and potential therapeutic vulnerability to immune checkpoint blockade: insights from genomic sequencing
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TN_cdi_doaj_primary_oai_doaj_org_article_1d4812b70d7d497fb50546116468f81b
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1d4812b70d7d497fb50546116468f81b
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ISSN
1756-994X
E-ISSN
1756-994X
DOI
10.1186/s13073-020-00753-2
