FX11 limits Mycobacterium tuberculosis growth and potentiates bactericidal activity of isoniazid thr...
FX11 limits Mycobacterium tuberculosis growth and potentiates bactericidal activity of isoniazid through host-directed activity
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Full title
Author / Creator
Publisher
England: The Company of Biologists Ltd
Journal title
Language
English
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Publication information
Publisher
England: The Company of Biologists Ltd
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Scope and Contents
Contents
Lactate dehydrogenase A (LDHA) mediates interconversion of pyruvate and lactate, and increased lactate turnover is exhibited by malignant and infected immune cells. Hypoxic lung granuloma in
-infected animals present elevated levels of
and lactate. Such alterations in the metabolic milieu could influence the outcome of host-
interactions....
Alternative Titles
Full title
FX11 limits Mycobacterium tuberculosis growth and potentiates bactericidal activity of isoniazid through host-directed activity
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TN_cdi_doaj_primary_oai_doaj_org_article_1d4e6545a6c14d64b47bf69114bc310d
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1d4e6545a6c14d64b47bf69114bc310d
Other Identifiers
ISSN
1754-8403
E-ISSN
1754-8411
DOI
10.1242/dmm.041954
