Defective dystrophic thymus determines degenerative changes in skeletal muscle
Defective dystrophic thymus determines degenerative changes in skeletal muscle
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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In Duchenne muscular dystrophy (DMD), sarcolemma fragility and myofiber necrosis produce cellular debris that attract inflammatory cells. Macrophages and T-lymphocytes infiltrate muscles in response to damage-associated molecular pattern signalling and the release of TNF-α, TGF-β and interleukins prevent skeletal muscle improvement from the inflamm...
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Full title
Defective dystrophic thymus determines degenerative changes in skeletal muscle
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TN_cdi_doaj_primary_oai_doaj_org_article_1d8c793c26284821978e4d5c5eaaacf0
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1d8c793c26284821978e4d5c5eaaacf0
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-22305-x
