Low dose Adenoviral Vammin gene transfer induces myocardial angiogenesis and increases left ventricu...
Low dose Adenoviral Vammin gene transfer induces myocardial angiogenesis and increases left ventricular ejection fraction in ischemic porcine heart
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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This preliminary study investigated if VEGFR-2 selective adenoviral Vammin (AdVammin) gene therapy could induce angiogenesis and increase perfusion in the healthy porcine myocardium. Also, we determined using a clinically relevant large animal model if AdVammin gene therapy could improve the function of a chronically ischemic heart. Low doses of Ad...
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Low dose Adenoviral Vammin gene transfer induces myocardial angiogenesis and increases left ventricular ejection fraction in ischemic porcine heart
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TN_cdi_doaj_primary_oai_doaj_org_article_1dbb7bbfe5c546bdb83e1bdc390a088d
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1dbb7bbfe5c546bdb83e1bdc390a088d
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-024-81773-5
