Simultaneous evolutionary expansion and constraint of genomic heterogeneity in multifocal lung cance...
Simultaneous evolutionary expansion and constraint of genomic heterogeneity in multifocal lung cancer
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Recent genomic analyses have revealed substantial tumor heterogeneity across various cancers. However, it remains unclear whether and how genomic heterogeneity is constrained during tumor evolution. Here, we sequence a unique cohort of multiple synchronous lung cancers (MSLCs) to determine the relative diversity and uniformity of genetic drivers up...
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Full title
Simultaneous evolutionary expansion and constraint of genomic heterogeneity in multifocal lung cancer
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TN_cdi_doaj_primary_oai_doaj_org_article_1dc6dd11f0204afa83eef84ead94c50d
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1dc6dd11f0204afa83eef84ead94c50d
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-017-00963-0
