The Josephin domain (JD) containing proteins are predicted to bind to the same interactors: Implicat...
The Josephin domain (JD) containing proteins are predicted to bind to the same interactors: Implications for spinocerebellar ataxia type 3 (SCA3) studies using Drosophila melanogaster mutants
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Publisher
Switzerland: Frontiers Media S.A
Journal title
Language
English
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Publisher
Switzerland: Frontiers Media S.A
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Contents
Spinocerebellar ataxia type 3, also known as Machado-Joseph disease (SCA3/ MJD), is the most frequent polyglutamine (polyQ) neurodegenerative disorder. It is caused by a pathogenic expansion of the polyQ tract, located at the C-terminal region of the protein encoded by the
ATXN3
gene. This gene codes for a deubiquitinating enzyme (DUB) that b...
Alternative Titles
Full title
The Josephin domain (JD) containing proteins are predicted to bind to the same interactors: Implications for spinocerebellar ataxia type 3 (SCA3) studies using Drosophila melanogaster mutants
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Author / Creator
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TN_cdi_doaj_primary_oai_doaj_org_article_1df483e0c8e844618a140fc7ce9a8004
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1df483e0c8e844618a140fc7ce9a8004
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ISSN
1662-5099
E-ISSN
1662-5099
DOI
10.3389/fnmol.2023.1140719
