Virtual Screening and Binding Analysis of Potential CD58 Inhibitors in Colorectal Cancer (CRC)
Virtual Screening and Binding Analysis of Potential CD58 Inhibitors in Colorectal Cancer (CRC)
About this item
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Author / Creator
Guo, Rong , Yu, Jiangnan and Guo, Zhikun
Publisher
Basel: MDPI AG
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Language
English
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Publisher
Basel: MDPI AG
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Scope and Contents
Contents
Human cell surface receptor CD58, also known as lymphocyte function-associated antigen 3 (LFA-3), plays a critical role in the early stages of immune response through interacting with CD2. Recent research identified CD58 as a surface marker of colorectal cancer (CRC), which can upregulate the Wnt pathway and promote self-renewal of colorectal tumor...
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Full title
Virtual Screening and Binding Analysis of Potential CD58 Inhibitors in Colorectal Cancer (CRC)
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TN_cdi_doaj_primary_oai_doaj_org_article_1df7680b41a942fd8cdb69fbd9e88279
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1df7680b41a942fd8cdb69fbd9e88279
Other Identifiers
ISSN
1420-3049
E-ISSN
1420-3049
DOI
10.3390/molecules28196819