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Alzheimer's disease as an autoimmune disorder of innate immunity endogenously modulated by tryptopha...

Alzheimer's disease as an autoimmune disorder of innate immunity endogenously modulated by tryptopha...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1e2d8b504a1f482e94ad2f6036b37c9c

Alzheimer's disease as an autoimmune disorder of innate immunity endogenously modulated by tryptophan metabolites

Publication information

Publisher

United States: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

Introduction
Alzheimer's disease (AD) is characterized by neurotoxic immuno‐inflammation concomitant with cytotoxic oligomerization of amyloid beta (Aβ) and tau, culminating in concurrent, interdependent immunopathic and proteopathic pathogeneses.
Methods
We performed a comprehensive series of in silico, in vitro, and in vivo studies expli...

Alternative Titles

Full title

Alzheimer's disease as an autoimmune disorder of innate immunity endogenously modulated by tryptophan metabolites

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_1e2d8b504a1f482e94ad2f6036b37c9c

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1e2d8b504a1f482e94ad2f6036b37c9c

Other Identifiers

ISSN

2352-8737

E-ISSN

2352-8737

DOI

10.1002/trc2.12283

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