CHD7 regulates bone-fat balance by suppressing PPAR-γ signaling
CHD7 regulates bone-fat balance by suppressing PPAR-γ signaling
About this item
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Author / Creator
Liu, Caojie , Xiong, Qiuchan , Li, Qiwen , Lin, Weimin , Jiang, Shuang , Zhang, Danting , Wang, Yuan , Duan, Xiaobo , Gong, Ping and Kang, Ning
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Chromodomain helicase DNA-binding protein 7 (CHD7), an ATP-dependent eukaryotic chromatin remodeling enzyme, is essential for the development of organs. The mutation of
CHD7
is the main cause of CHARGE syndrome, but its function and mechanism in skeletal system remain unclear. Here, we show conditional knockout of
Chd7
in bone marrow me...
Alternative Titles
Full title
CHD7 regulates bone-fat balance by suppressing PPAR-γ signaling
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_1e58001fa8164d9fb718b2e98336af10
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1e58001fa8164d9fb718b2e98336af10
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-022-29633-6
